Cheshire is a skilled hand-to-hand combatant, and is one of the premiere martial artists and hand-to-hand combatants in the DC Universe. She is trained in several martial arts thought forever lost. In addition, Cheshire is also an expert triple-jointed acrobat, and uses this skill to move quickly and unexpectedly, and to also augment her fighting abilities. Of bigger concern are her artificial fingernails, which she dips in several varieties of poisons. She gives her weapons and other accessories a similar treatment.